李雅芬,牛爱青,康立丽.磁共振T2-Map的单、双指数拟合方法[J].中国医学影像技术,2010,26(2):347~350
磁共振T2-Map的单、双指数拟合方法
Single-exponential and dual-exponential fitting methods of MR T2-Map
投稿时间:2009-07-09  修订日期:2009-10-15
DOI:
中文关键词:  磁共振成像  T2-Map  线性拟合  非线性回归
英文关键词:Magnetic resonance image  T2-Map  Linear fitting  Non-linear regression
基金项目:
作者单位E-mail
李雅芬 南方医科大学生物医学工程学院医学工程系,广东 广州 510515  
牛爱青 南方医科大学生物医学工程学院医学工程系,广东 广州 510515  
康立丽 南方医科大学生物医学工程学院医学工程系,广东 广州 510515 kllysz@fimmu.com 
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中文摘要:
       目的 探讨MR图像单指数和双指数拟合的T2-Map方法,获得每个像素点的T2信息。方法 对不同TE条件下的一系列MR图像利用单、双指数拟合方法得到T2-Map图像。采用线性拟合和非线性回归方法实现对MR图像的每个像素点的单指数拟合和定点双指数拟合,得到T2-Map图像;上述计算过程是在MATLAB平台上开发T2-Map的计算软件,根据应用需求设计并实现计算、显示和存储等功能。结果 得到了单、双指数拟合方法的T2-Map计算软件,可用于计算不同组织的T2值,得到T2-Map。结论 利用单指数线性拟合方法得到T2-Map图像方便、快捷,但不能很好地反映一些组织成分混合较多的区域;在出现组织明显混合的情形时,双指数拟合的方法可以计算出两个不同的T2值,使得分析结果更加精确,但是计算速度较慢,双指数T2-Map是单指数T2-Map计算方法的有益补充。
英文摘要:
      Objective To assess the single-exponential and dual-exponential fitting methods of MR T2-Map, and to get T2 value of each pixel. Methods Single and dual-exponential methods with linear fitting and non-linear regression fitting techniques were used for a series images with different TE; then T2-Map images were achieved. T2-Map software was realized on MATLAB and it had the function of compute, display, save and so on. Results T2-Map software with single-exponential and dual-exponential fitting methods was achieved, able to calculate T2 value of tissues everywhere and form the T2-Map image. Conclusion Single-exponential T2-Map method is convenient, having obvious merit-high speed, but can not show the area with obvious different contents very well. However, dual-exponential fitting method can deal with this question with providing different T2 values, thus is accurate with the sacrifice of costing too much time. Dual-exponential fitting method of T2-Map is a beneficial supplement to single-exponential method.
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