| 安彦虹,齐志刚,戎冬冬,赵志莲,卢洁.成人缺血缺氧性脑病的MRI特征分析[J].中国医学影像技术,2020,36(6): |
| 成人缺血缺氧性脑病的MRI特征分析 |
| Characteristics of MRI Findings on adult hypoxic-ischemic encephalopathy |
| 投稿时间：2019-05-12 修订日期：2020-06-19 |
| DOI： |
| 中文关键词: 缺血缺氧性脑病 成人 磁共振成像 扩散加权成像 |
| 英文关键词:Hypoxic-ischemic encephalopathy Adult Magnetic resonance imaging Diffusion weighted imaging |
| 基金项目:国家重点研发计划项目（编号2016YFC0107107）；北京市科学技术委员会资助项目(编号Z171100000117001)；北京市医院管理局“登峰”计划（编号DFL20180802） |
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| 中文摘要: |
| 目的 分析成人缺血缺氧性脑病患者的MRI表现及其特征。方法 收集2013年1月至2018年9月首都医科大学宣武医院诊治的18例缺血缺氧性脑病患者的临床与MRI资料，包括9例男性，9例女性；年龄19～73岁，中位年龄43岁；病程1天～21个月。患者因各种原因导致缺血缺氧后予以MRI检查。结果 18例患者中有17例MRI检查发现脑内异常信号，累及部位包括：大脑皮层、皮层下白质、深部白质、侧脑室周围白质、胼胝体、基底节、海马、丘脑、桥脑及小脑；其中9例患者出现全脑萎缩，5例T1WI显示高信号，9例DWI显示扩散受限，5例行MRI增强检查的患者中1例大脑皮层见脑回样轻度强化。1例患者在MRI上未见明显病变。结论 缺血缺氧性脑病MRI检查绝大多数可以发现脑内异常信号，且累计多个脑区，也可表现为正常。MRI检查结果不仅可以反映脑缺血缺氧的严重程度，还可预测和评估患者的预后及治疗效果。 |
| 英文摘要: |
| Objective To investigate the MRI features of adult with hypoxic-ischemic encephalopathy. Methods A total of 18 adult with hypoxic-ischemic encephalopathy admitted to Xuanwu Hospital Capital Medical University from January 2013 to September 2018 were enrolled in this study. Among the 18 patients，9 were female and 9 were male.Their age ranged from 19 to 73 years with a median age of 43 years. The clinical course was 1 day to 21 months. Their MRI findings were analyzed retrospectively. Results Patients with abnormal MRI manifestation accounted for 94.44% (17/18), involving cerebral cortex, subcortical white matter, deep white matter, lateral ventricle, corpus callosum, basal ganglia, hippocampus, thalamus, pons and cerebellum. Total brain atrophy were show in 9 cases. Unenhanced T1WI showed hyperintense along the cerebral cortex or basal ganglia in 5 cases. Restricted diffusion showed in 9 cases. and 1 of the 5 cases who underwent enhanced MRI showed mild gyrus enhancement in cerebral cortex. MRI showed no obvious lesions in 1 case. Conclusion MRI findings of hypoxic-ischemic encephalopathy may be normal or multiple sites. MRI features can not only reflect the severity of hypoxic-ischemic encephalopathy, but also predict and evaluate the prognosis and treatment effect of patients. |
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