肖悦,杜名,辛军.比较PET/CT与PET/MRI诊断成人淋巴瘤[J].中国医学影像技术,2020,36(8):1187~1191
比较PET/CT与PET/MRI诊断成人淋巴瘤
Comparison on whole-body PET/CT and PET/MRI in diagnosis of adult lymphoma
投稿时间:2019-11-18  修订日期:2020-05-06
DOI:10.13929/j.issn.1003-3289.2020.08.015
中文关键词:  淋巴瘤  正电子发射断层显像  体层摄影术,X线计算机
英文关键词:lymphoma  positron-emission tomography  tomography,X-ray computed
基金项目:辽宁省(科技厅)重点研发计划指导计划攻关项目(2017225030)、沈阳科技计划项目(18014423)。
作者单位E-mail
肖悦 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004  
杜名 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004  
辛军 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004 xinj@sj-hospital.org 
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中文摘要:
      目的 比较PET/CT与PET/MRI诊断成人淋巴瘤的效能。方法 前瞻性观察45例淋巴瘤患者,行全身PET/CT和PET/MR检查,分别由2名医师独立评估PET/CT和PET/MRI,获得病灶最大标准摄取值(SUVmax)及对应D值、D*值和f值,分析两种模式的诊断效能及分期差异。结果 PET/CT与PET/MRI均测出55个淋巴结和5个结外病灶的SUVmax,基于体素内不相干运动(IVIM)模型测出39个病灶的对应值。医师间对阳性病灶检测率一致性极强(k=1.000),PET/CT与PET/MRI的一致性极强(k=0.956);对于淋巴瘤分期,PET/CT与PET/MRI一致性极强(k=0.965);PET/CT与PET/MRI的SUVmax呈高度相关(r=0.892,P<0.001),D值与SUV值低度相关(r=-0.312,P<0.050),f值与SUV值呈中度相关(r=0.520,P<0.001)。结论 PET/CT与PET/MRI对成人均有良好诊断效能,PET/MRI可提高淋巴瘤诊断及分期的准确率,多参数联合可预测和评估肿瘤异质性。
英文摘要:
      Objective To compare the diagnostic efficacy of PET/CT and PET/MRI for adult lymphoma. Methods A total of 45 lymphoma patients who underwent systemic PET/CT and PET/MRI examinations. Data of PET/CT were evaluated by 2 readers independently, and PET/MRI were interpreted by 2 other readers,respectively. The maximal standardized uptake value (SUVmax), D value, D* value and f value corresponding to the maximum SUVmax were obtained, and the differences of diagnostic efficacy and staging of PET/CT and PET/MRI were analyzed. Results Both PET/CT and PET/MRI detected SUVmax in 55 lymph nodes and 5 extra-node lesions. Thirty-nine lesions were identified on intravoxel incoherent motion (IVIM). For positive lesion detection, reader agreement was perfect between 2 readers and almost perfect between PET/CT and PET/MRI (k=0.956). For lymphoma staging, PET/CT was strongly consistent with PET/MRI (k=0.965). SUVmax from PET/CT and PET/MRI was significantly correlated (r=0.892, P<0.001), while weak correlation was demonstrated between D value and SUVmax (r=-0.312, P<0.050) and moderate correlation was demonstrated between f value and SUVmax (r=0.520, P<0.001). Conclusion PET/MRI is comparable to PET/CT in diagnosis and staging in lymphoma, which can improve the accuracy of diagnosis and staging of lymphoma and moreover predict and evaluate the heterogeneity of tumor through combination of multiple parameters.
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