徐臣,孙洪赞.18F-FDG PET/CT参数联合临床特征预测手术治疗早期宫颈癌患者预后[J].中国医学影像技术,2020,36(1):106~110
18F-FDG PET/CT参数联合临床特征预测手术治疗早期宫颈癌患者预后
18F-FDG PET/CT parameters combined with clinical features in predicting prognosis of patients with early cervical cancer
投稿时间:2019-03-11  修订日期:2019-08-28
DOI:10.13929/j.issn.1003-3289.2020.01.030
中文关键词:  子宫颈肿瘤  18F氟脱氧葡萄糖  淋巴结  预后
英文关键词:uterine cervical neoplasms  Fluorodeoxyglucose F18  lymph nodes  prognosis
基金项目:国家自然科学基金青年科学基金项目(81401438)、辽宁省重点研发计划指导计划项目(2017225012)。
作者单位E-mail
徐臣 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004  
孙洪赞 中国医科大学附属盛京医院放射科, 辽宁 沈阳 110004 sunhongzan@126.com 
摘要点击次数: 162
全文下载次数: 116
中文摘要:
      目的 探讨18F-FDG PET/CT参数联合临床特征对预测早期宫颈癌患者手术治疗后预后的价值。方法 回顾性分析70例术前接受18F-FDG PET/CT检查的早期宫颈癌患者,比较术后复发组与无复发组间代谢参数的差异,评价18F-FDG PET/CT参数结合临床特征对预后的预测价值。结果 术后平均随访(53.86±15.74)个月,期间11例(11/70,15.71%)肿瘤复发。相关18F-FDG PET/CT参数中,峰值标准摄取值(SUVpeak)可预测肿瘤复发(AUC=0.672,P=0.03)。多因素比例风险模型(Cox)显示,淋巴结转移状态及SUVpeak是最主要的预测因素。结论 SUVpeak和淋巴结转移状态是评价手术治疗后早期宫颈癌患者预后的主要指标。
英文摘要:
      Objective To explore the prognostic value of 18F-FDG PET/CT parameters combined with clinical features in predicting prognosis of early cervical cancer patients after surgical operation. Methods A total of 70 cervical cancer patients who underwent 18F-FDG PET/CT before operation were collected and retrospectively analyzed. Differences of metabolic parameters were compared between relapsed patients (relapse group) and non-recurrent ones (non-recurrent group). The predictive value of 18F-FDG PET/CT parameters combined with clinical features for prognosis were analyzed. Results The mean follow-up time was (53.86±15.74) months, and recurrence of cervical cancer occurred in 11 patients (11/70, 15.71%). The peak standard uptake value (SUVpeak) was the only 18F-FDG PET/CT parameter predicting recurrence (AUC=0.672, P=0.03). Multivariate proportional hazards model (Cox) showed that lymph node metastatic status and SUVpeak were the most important predictors. Conclusion SUVpeak and lymph node metastatic status are main indicators for evaluating prognosis of patients with early cervical cancer after surgical operation.
查看全文  查看/发表评论  下载PDF阅读器