陈筱雪,马江伟,贺倩倩,王琮,王凤翎,范林艳,杨少玲,赵坤.分层应变评估急性冠状动脉综合征患者经皮冠状动脉介入术后心肌功能[J].中国医学影像技术,2020,36(1):21~26
分层应变评估急性冠状动脉综合征患者经皮冠状动脉介入术后心肌功能
Layers-strain on assessing myocardial function in acute coronary syndrome patients after percutaneous coronary intervention
投稿时间:2019-05-08  修订日期:2019-12-13
DOI:10.13929/j.issn.1003-3289.2020.01.005
中文关键词:  急性冠状动脉综合征  经皮冠状动脉介入治疗  斑点追踪成像  分层应变  心肌功能
英文关键词:acute coronary syndrome  percutaneous coronary intervention  speckle tracking imaging  layers strain  myocardial function
基金项目:
作者单位E-mail
陈筱雪 安徽理工大学医学院, 安徽 淮南 232000  
马江伟 安徽理工大学附属奉贤区中心医院心血管内科, 上海 201499  
贺倩倩 安徽理工大学医学院, 安徽 淮南 232000  
王琮 安徽理工大学医学院, 安徽 淮南 232000  
王凤翎 安徽理工大学附属奉贤区中心医院心脏血管超声科, 上海 201499  
范林艳 安徽理工大学附属奉贤区中心医院心脏血管超声科, 上海 201499  
杨少玲 安徽理工大学附属奉贤区中心医院心脏血管超声科, 上海 201499 drysl@163.com 
赵坤 安徽理工大学医学院, 安徽 淮南 232000  
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中文摘要:
      目的 观察纵向分层应变评估急性冠状动脉综合征(ACS)患者经皮冠状动脉介入(PCI)术后左心室心肌功能的临床价值。方法 收集25例成功接受PCI的ACS患者(PCI组)及25名健康志愿者(对照组)。应用M型、双平面Simpson法、组织多普勒及室壁分层应变分别评价2组左心功能及左心室壁3层心肌运动。结果 PCI组左心室壁各层纵向应变及整体纵向应变由心内膜向心外膜逐渐降低,且均低于对照组(P均<0.05)。2组心内膜与心外膜间整体纵向应变均存在一定跨壁梯度(△GLS),但PCI组△GLS绝对值低于对照组(P<0.05)。结论 PCI术后ACS患者左心室壁纵向应变从心内膜向心外膜逐渐减低;纵向分层应变是评价PCI术后ACS患者心肌和左心功能受损的敏感方法。
英文摘要:
      Objective To explore the clinical value of longitudinal layers-strain technology for assessing myocardial function in acute coronary syndrome (ACS) patients after percutaneous coronary intervention (PCI). Methods Twenty-five ACS patients who underwent successful PCI (PCI group) and 25 normal subjects (control group) were collected. M-mode echocardiography, biplane Simpson, tissue Doppler imaging and longitudinal layers-strain were used to analyze left ventricular function and myocardial function respectively in both groups. Results Longitudinal layers strain and global longitudinal layers strain in PCI group decreased gradually from endocardium to epicardium, and all parameters reduced compared with those of control group (all P<0.05). The gradient of global longitudinal strain between endocardium and epicardium (△GLS) existed in both groups, while the absolute value of △GLS apparently reduced in PCI group compared with control group (P<0.05). Conclusion Longitudinal strain decreased from endocardium to epicardium in ACS patients after PCI. Longitudinal layers-strain might be a sensitive index of myocardial and left ventricular dysfunction in ACS patients after PCI.
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