吕文豪,聂芳,朱阳阳,张雪云,许爱玲,汪延芳.CEUS评估不同大小BI-RADS 4类乳腺病灶恶性风险[J].中国医学影像技术,2019,35(11):1673~1677
CEUS评估不同大小BI-RADS 4类乳腺病灶恶性风险
CEUS in evaluation of malignant risk of BI-RADS 4 levels of breast lesions with different sizes
投稿时间:2019-01-25  修订日期:2019-09-25
DOI:10.13929/j.1003-3289.201901158
中文关键词:  乳腺肿瘤  超声检查,乳房  乳腺影像报告和数据系统
英文关键词:breast neoplasms  ultrasonography, mammary  breast imaging reporting and data system
基金项目:
作者单位E-mail
吕文豪 兰州大学第二医院超声科, 甘肃 兰州 730030  
聂芳 兰州大学第二医院超声科, 甘肃 兰州 730030 Fang-nie@163.com 
朱阳阳 兰州大学第二医院超声科, 甘肃 兰州 730030  
张雪云 兰州大学第二医院超声科, 甘肃 兰州 730030  
许爱玲 兰州大学第二医院超声科, 甘肃 兰州 730030  
汪延芳 兰州大学第二医院超声科, 甘肃 兰州 730030  
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中文摘要:
      目的 探讨CEUS对不同大小乳腺影像报告和数据系统(BI-RADS)4类乳腺病灶恶性风险的评估价值。方法 回顾性分析经获病理结果的直径≤ 2 cm(n=120)与直径>2 cm(n=63)的BI-RADS 4类乳腺良恶性病灶的CEUS特征,采用二元Logistic回归分析筛选能够预测恶性病灶的CEUS特征参数。结果 直径≤ 2 cm良恶性病灶的CEUS增强形态、增强程度、增强均匀性、灌注模式、滋养血管、增强范围扩大及初始增强速度、消退速度差异均有统计学意义(P均<0.05),回归分析筛选出增强范围扩大、有滋养血管与BI-RADS 4类乳腺恶性病灶独立相关(P均<0.05);直径>2 cm良恶性病灶的增强形态、灌注模式、滋养血管、增强范围扩大及初始增强速度差异均有统计学意义(P均<0.05),回归分析筛出有滋养血管、灌注模式呈向心性、增强范围扩大与BI-RADS 4类乳腺恶性病灶独立相关(P均<0.05)。结论 CEUS能够用于评估BI-RADS 4类不同大小乳腺病灶的恶性风险。
英文摘要:
      Objective To evaluate the value of CEUS in evaluating of malignant risk of breast imaging report and data system (BI-RADS) 4 levels of breast lesions with different sizes. Methods The CEUS characteristics of BI-RADS 4 levels of the benign and malignant breast lesions with diameter ≤ 2 cm (n=120) and diameter >2 cm (n=63) were analyzed retrospectively. Binary Logistic regression analysis was used to screen CEUS characteristic parameters that could predict malignant lesions. Results There were differences of enhanced shape, enhanced intensity, homogeneity, perfusion pattern, nourishing vessels, enhanced area expansion, initial rates and fading rates between the benign and malignant lesions with diameter ≤ 2 cm (all P<0.05); regression analysis showed that enhanced area expansion and nourishing vessels were independently correlated with malignant breast lesions of BI-RADS 4 levels (both P<0.05). There were differences of enhanced shape, perfusion pattern, nourishing vessels, enhanced area expansion and initial rates between the benign and malignant lesions with diameter>2 cm (all P<0.05); regression analysis showed that nourishing vessels, centripetal enhancement pattern and enhanced area expansion were independently correlated with malignant breast lesions of BI-RADS 4 levels (all P<0.05). Conclusion CEUS can be used to evaluate the malignant risk of BI-RADS 4 levels of breast lesions with different sizes.
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