| 罗向红,张健慧,邵思惠,闫敏,吴蓉,杜联芳,李朝军.超声剪切波频散成像评估颈动脉黏弹性[J].中国医学影像技术,2019,35(9):1321~1326 |
| 超声剪切波频散成像评估颈动脉黏弹性 |
| Ultrasound shear wave dispersion imaging in evaluation of carotid viscoelasticity |
| 投稿时间：2019-02-15 修订日期：2019-05-30 |
| DOI：10.13929/j.1003-3289.201902043 |
| 中文关键词: 剪切波频散 颈动脉 脉搏波传播速度 黏弹性 超声检查 |
| 英文关键词:shear wave dispersion carotid arteries pulse wave velocity viscoelasticity ultrasonography |
| 基金项目:上海市科学技术委员会医学引导类科技项目（16411969300）、上海市卫生和计划生育委员会基金（201640043）、促进市级医院临床技能与临床创新能力三年行动计划（16CR3105B）、上海市松江区科技攻关项目（18sjkjgg72、18sjkjgg53）、上海交通大学医工交叉研究基金（YG2015MS28）。 |
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| 中文摘要: |
| 目的 探讨超声剪切波频散技术检测颈动脉黏弹性的可行性。方法 将45例患者根据年龄分为≥ 50岁组（n=23）和<50岁组（n=22）。采用剪切波频散技术测量颈总动脉浅壁和深壁的剪切波弹性模量值（SWES和SWED）、颈总动脉浅壁和深壁的剪切波频散值（SWDS和SWDD）；同时测量颈总动脉脉搏波传播速度（PWV）。比较2组间各黏弹性指标差异，并分析其与年龄、血压和PWV的相关性。结果 经体质量指数、收缩压（SBP）和舒张压（DBP）校正前后，<50岁组SWES、SWED、SWDS和SWDD均大于≥ 50岁组（P均<0.05）。颈总动脉剪切波弹性模量值与年龄、SBP、DBP和PWV呈负相关（r=-0.282、-0.374、-0.321、-0.256，P均<0.05）。≥ 50岁组中颈总动脉剪切波频散值与PWV呈负相关（r=-0.393，P=0.038），<50岁组中与SBP呈正相关（r=0.366，P=0.048）。结论 超声剪切波频散技术可无创、定量评估颈总动脉黏弹性。 |
| 英文摘要: |
| Objective To observe the feasibility of ultrasound shear wave dispersion imaging (USWD) in evaluating carotid viscoelasticity. Methods Totally 45 volunteers were recruited and divided into 2 groups according to age, i.e. ≥ 50 years old group (n=23) and <50 years old group (n=22). Four shear wave viscoelastic modulus of the common carotid artery (CCA), including shear wave elastic modulus values of the superficial and deep walls (SWES and SWED), shear wave dispersion values of superficial and deep walls (SWDS and SWDD) were obtained using USWD, respectively. In addition, the pulse wave velocity (PWV) was measured. The viscoelastic indexes were compared between the two groups, and the correlations with age, blood pressure and PWV were analyzed. Results Before and after adjusted with body mass index, systolic blood pressure (SBP) and diastolic blood pressure (DBP), SWES, SWED, SWDS and SWDD were higher in <50 years old group than those in ≥ 50 years old group (all P<0.05). Among all subjects, SWE was negatively correlated with age, SBP, DBP and PWV, respectively (r=-0.282, -0.374, -0.321, -0.256, all P<0.05). SWD was negatively correlated with PWV in ≥ 50 years old group (r=-0.393, P=0.038), while positively correlated with SBP in <50 years old group (r=0.366, P=0.048). Conclusion The viscoelasticity of arterial wall can be non-invasively and quantitatively assessed with USWD. |
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