| 郝振亮,王俊清,任超,赵晓斌.静脉注射18F-FDG注射液后冲洗注射器对残留剂量及肝脏标准化摄取值的影响[J].中国医学影像技术,2019,35(7):1091~1094 |
| 静脉注射18F-FDG注射液后冲洗注射器对残留剂量及肝脏标准化摄取值的影响 |
| Impact of syringe saline flush after injection of 18F-FDG on residual dose and standardized uptake value of liver |
| 投稿时间：2019-01-12 修订日期：2019-05-28 |
| DOI：10.13929/j.1003-3289.201901081 |
| 中文关键词: 氟脱氧葡萄糖F18 注射器 残留量 标准化摄取值 正电子发射体层摄影术 |
| 英文关键词:fludeoxyglucose F 18 syringes residual dose standardized uptake value positron-emission tomography |
| 基金项目:国家自然科学基金（81527805）。 |
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| 中文摘要: |
| 目的 探讨PET/CT检查时静脉注射18F-FDG注射液后冲洗注射器对放射性药物残留剂量以及肝脏标准化摄取值（SUV）的影响。方法 收集接受PET/CT检查的50例患者，根据注药方式分为对照组（n=25）和实验组（n=25）。采用23G头皮针建立静脉通路，注射18F-FDG注射液后，对照组直接用5 ml生理盐水冲洗管道；实验组先用1 ml生理盐水冲洗管道，然后用2 ml生理盐水冲洗注射器，最后用剩余2 ml再次冲洗管道。比较2组间18F-FDG注射后残留剂量以及肝脏SUV平均值（SUVmean）和SUV最大值（SUVmax）的差异。结果 实验组总残留剂量[（0.22±0.08）mCi]、注射器内残留剂量[（0.19±0.07）mCi]和静脉通道内残留剂量[（0.03±0.02）mCi]均小于对照组（P均<0.01）。实验组与对照组肝脏3个不同层面（第二肝门层面、门静脉左支层面、第一肝门层面）的SUVmean和SUVmax差异均无统计学意义（P均>0.05）。结论 冲洗注射器能减少18F-FDG注射液残留量。注射器内少量放射性药物残留尚不足以引起肝脏SUV变化，但进一步规范18F-FDG注射操作流程仍属必要。 |
| 英文摘要: |
| Objective To investigate the impact of saline flush for syringe after 18F-FDG injection on the residual dose of 18F-FDG and the standardized uptake value (SUV) of liver during PET/CT examination. Methods A total of 50 patients who underwent PET/CT examination were enrolled and divided into control group (n=25) and experimental group (n=25) according to different injection methods. Device system of the vein passage was established with 23 gauge scalp needle. In control group, the intravenous line was directly flushed with 5 ml physiological saline after 18F-FDG injection, while in experimental group, firstly the intravenous line was flushed with 1 ml saline, then the syringe was flushed with 2 ml saline, finally the intravenous line was flushed again with the residual 2 ml saline. The residual dose of 18F-FDG and SUVmean and SUVmax of liver were compared between the two groups. Results The total residual dose ([0.22±0.08]mCi), syringe residual dose ([0.19±0.07]mCi) and intravenous channel residual dose ([0.03±0.02]mCi) in the experimental group were all lower than those in control group (all P<0.01). There was no significant difference of SUVmean nor SUVmax between experimental group and control group at 3 different levels of the liver (level of the second liver porta, level of the left portal vein and level of the first liver porta, all P>0.05). Conclusion Flushing the syringe can reduce residual dose of 18F-FDG injection. A small amount of radiopharmaceuticals retention in the syringe may not affect SUV for liver, but further standardization of the operation process of 18F-FDG injection is still necessary. |
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