庄霞梅,金科,李君伟,尹燕,王海,李晓明,尹一伟.儿童朗格汉斯细胞组织细胞增生症累及肝脏影像学表现[J].中国医学影像技术,2019,35(6):862~866
儿童朗格汉斯细胞组织细胞增生症累及肝脏影像学表现
Imaging manifestations of liver Langerhans cell histiocytosis
投稿时间:2018-09-15  修订日期:2019-04-05
DOI:10.13929/j.1003-3289.201809084
中文关键词:  组织细胞增多症,郎格尔汉斯细胞  儿童  肝脏  体层摄影术,X线计算机  磁共振成像
英文关键词:histiocytosis, Langerhans-cell  child  liver  tomography, X-ray computed  magnetic resonance imaging
基金项目:湖南省自然科学基金-青年基金项目(2018JJ3271)。
作者单位E-mail
庄霞梅 湖南省儿童医院放射科, 湖南 长沙 410007  
金科 湖南省儿童医院放射科, 湖南 长沙 410007 jinke001@sina.com 
李君伟 湖南省儿童医院放射科, 湖南 长沙 410007  
尹燕 湖南省儿童医院放射科, 湖南 长沙 410007  
王海 湖南省儿童医院放射科, 湖南 长沙 410007  
李晓明 湖南省儿童医院放射科, 湖南 长沙 410007  
尹一伟 湖南省儿童医院放射科, 湖南 长沙 410007  
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中文摘要:
      目的 探讨儿童朗格汉斯细胞组织细胞增生症(LCH)累及肝脏的CT、MRI表现。方法 回顾性分析确诊为LCH侵犯肝脏的22例患儿的CT及MRI表现。结果 22例患儿均表现肝脏肿大。20例Glisson鞘增宽及汇管区轨道征、晕征,其中16例CT呈低密度,5例CT增强扫描呈轻、中度强化,4例MRI表现为T2WI高信号,2例MRI增强后轻度强化。14例表现为肝内多发结节,直径约0.51~2.35 cm,其中10例沿门静脉分布、4例呈弥漫性分布;11例CT呈低密度,5例CT增强呈轻、中度强化,3例T1WI呈低信号、T2WI呈高信号,2例MR增强扫描轻度强化,较大结节呈环形强化。8例肝内胆管呈节段性狭窄及不同程度扩张。结论 儿童LCH累及肝脏的CT、MRI表现具有一定特征性。
英文摘要:
      Objective To investigate CT and MRI manifestations of Langerhans cell histiocytosis (LCH) involving the liver in children. Methods CT and MRI findings of 22 children with LCH involving the liver were retrospectively analyzed. Results Hepatomegaly was found in all 22 children, while widening of Glisson sheath and track sign and halo sign of portal area were observed in 20 cases. CT showed low density in 16 cases, 5 cases showed mild to moderate enhancement, and MRI showed high signal intensity in 4 cases and 2 cases showed mild enhancement of T2WI. Fourteen children presented multiple nodules in the liver, with diameters of 0.51-2.35 cm, distributed along the portal vein in 10 cases and diffusely distributed in 4 cases. Among them, CT showed low densities in 11 cases and 5 cases showed mild to moderate enhancement, while T1WI showed low signal intensities and T2WI showed high signal intensities in 3 cases and 2 cases showed mild enhancement. Intrahepatic bile duct alternative stenoses/dilatation were noticed in 8 cases. Conclusion CT and MRI findings of LCH involving the liver in children have certain characteristics.
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