| 石富文,杨敏,顾小宁,刘芳,刘冬梅,白文佩,赵率红.经阴道四维超声子宫输卵管造影评估不孕症患者输卵管通畅性[J].中国医学影像技术,2019,35(5):730~734 |
| 经阴道四维超声子宫输卵管造影评估不孕症患者输卵管通畅性 |
| Transvaginal four-dimensional hysterosalpingo-contrast sonography in evaluation on patency of fallopian tubes in infertile patients |
| 投稿时间：2018-10-28 修订日期：2019-03-13 |
| DOI：10.13929/j.1003-3289.201810161 |
| 中文关键词: 输卵管 不育,女(雌)性 四维超声子宫输卵管造影 |
| 英文关键词:fallopian tube infertility, female four-dimensional hysterosalpingo-contrast sonography |
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| 中文摘要: |
| 目的 探讨经阴道四维超声子宫输卵管造影（4D-HyCoSy）诊断不孕症患者输卵管通畅性的应用价值。方法 回顾性对比分析112例不孕症患者经阴道4D-HyCoSy和腹腔镜亚甲蓝通液（LC）诊断输卵管通畅性的结果，计算4D-HyCoSy诊断输卵管阻塞的敏感度、特异度、阳性预测值、阴性预测值、阳性似然比、阴性似然比和AUC，并评价4D-HyCoSy与LC诊断输卵管通畅性的一致性。结果 112例不孕症患者共检查218条输卵管。以LC结果为金标准，4D-HyCoSy诊断输卵管通畅、通而不畅及阻塞的符合率分别为88.64%（39/44）、72.09%（62/86）、89.77%（79/88），总符合率为82.57%（180/218）；4D-HyCoSy诊断输卵管阻塞的敏感度、特异度、阳性预测值、阴性预测值、阳性似然比及阴性似然比分别为80.61%（79/98）、92.50%（111/120）、89.77%（79/88）、85.38%（111/130）、10.75和0.19，AUC为0.87（P<0.01）。4D-HyCoSy与LC诊断输卵管通畅性的一致性较好（Kappa=0.74）。结论 4D-HyCoSy与LC诊断输卵管通畅性的一致性较好，4D-HyCoSy诊断输卵管阻塞具有较高的特异度。 |
| 英文摘要: |
| Objective To explore the application value of four-dimensional hysterosalpingo-contrast sonography (4D-HyCoSy) with transvaginal ultrasound in evaluation of fallopian tube patency in infertile patients. Methods Clinical data of 112 infertile patients who underwent 4D-HyCoSy and laparoscopic chromopertubation using methylene blue (LC) were retrospectively analyzed. The sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio, negative likelihood ratio and AUC of 4D-HyCoSy in diagnosis of tubal obstruction were calculated. Then the consistency between 4D-HyCoSy and LC in diagnosis of fallopian tube patency was evaluated. Results A total of 218 fallopian tubes were examined in 112 infertile patients. Taken LC results as gold standards, the coincidence rates of 4D-HyCoSy in diagnosis of tubal patency, partially obstructed and completely obstructed were 88.64% (39/44), 72.09% (62/86) and 89.77% (79/88), respectively, and the overall coincidence rate was 82.57% (180/218). The sensitivity, specificity, positive predictive value, negative predictive value, positive likelihood ratio and negative likelihood ratio of 4D-HyCoSy in diagnosis of tubal obstruction were 80.61% (79/98), 92.50% (111/120), 89.77% (79/88), 85.38% (111/130), 10.75 and 0.19, respectively, AUC was 0.87 (P<0.01). 4D-HyCoSy had higher consistency with LC in diagnosis of tubal patency (Kappa=0.74). Conclusion 4D-HyCoSy is consistent with LC in diagnosis of fallopian tube patency, which has high specificity in diagnosing tubal obstruction. |
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