郭油油,李咏梅,王静杰,韩永良,孔丽娜,陈晓娅.双源CT能谱参数定性诊断甲状腺乳头状癌术后颈部转移淋巴结[J].中国医学影像技术,2019,35(5):669~672
双源CT能谱参数定性诊断甲状腺乳头状癌术后颈部转移淋巴结
Dual-source CT energy parameters in qualitative diagnosis of metastatic cervical lymph nodes after surgical resection of papillary thyroid carcinoma
投稿时间:2018-08-22  修订日期:2019-03-07
DOI:10.13929/j.1003-3289.201808147
中文关键词:  甲状腺肿瘤    淋巴结  体层摄影术,X线计算机  能谱成像
英文关键词:thyroid neoplasms  neck  lymph nodes  tomography, X-ray computed  spectral imaging
基金项目:重庆市卫健委医学科研重点课题(2016ZDXM002)。
作者单位E-mail
郭油油 重庆医科大学附属第一医院放射科, 重庆 400016  
李咏梅 重庆医科大学附属第一医院放射科, 重庆 400016 lymzhang70@aliyun.com 
王静杰 重庆医科大学附属第一医院放射科, 重庆 400016  
韩永良 重庆医科大学附属第一医院放射科, 重庆 400016  
孔丽娜 重庆医科大学附属第一医院放射科, 重庆 400016  
陈晓娅 重庆医科大学附属第一医院放射科, 重庆 400016  
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中文摘要:
      目的 探讨双源CT能谱参数对定性诊断甲状腺乳头状癌(PTC)术后颈部转移淋巴结的价值。方法 选取PTC术后颈部淋巴结肿大患者30例、共74枚肿大淋巴结,其中49枚为转移性淋巴结(转移组),25枚为非转移性淋巴结(非转移组)。另选30例良性病变患者作为良性增生组(30枚良性肿大淋巴结)。行双源CT平扫及增强扫描,测量并比较组间平扫、动脉期、静脉期碘浓度(分别记为IC平扫、IC动脉、IC静脉)及标准化碘浓度(NIC)、能谱曲线斜率(K)。结果 3组间IC平扫、IC动脉、IC静脉、NIC及K值差异均有统计学意义(P均<0.05);转移组IC平扫低于非转移组及良性增生组,IC动脉、NIC及K值均高于非转移组及良性增生组(P均<0.05);非转移组与良性增生组间IC平扫、IC动脉、IC静脉、NIC及K值差异均无统计学意义(P均>0.05)。结论 双源CT能谱参数可用于定性诊断PTC术后颈部转移淋巴结。
英文摘要:
      Objective To explore the diagnostic value of dual-source CT energy parameters in qualitative diagnosis of metastatic cervical lymph nodes after surgical resection of thyroid papillary carcinoma (PTC). Methods Totally 30 postoperative PTC patients with 74 enlarged cervical lymph nodes were enrolled, including 49 metastatic lymph nodes (metastatic group) and 25 non metastasis lymph nodes (non-metastatic group). In addition, 30 cases with benign enlarged cervical lymph nodes were taken as benign group. All subjects underwent dual-source CT scanning. The iodine concentration value of nonenhanced phase (ICNP), arterial phase (ICAP) and venous phase (ICVP), normalized iodine concentration (NIC) and slope of energy spectrum curve (K) were detected and compared among 3 groups. Results There were significant differences in ICNP, ICAP, ICVP, NIC and K among 3 groups (all P<0.05). ICNP in metastatic group was lower than that in non-metastatic group and benign group (both P<0.05), while ICAP, NIC and K were higher than those in non-metastatic group and benign group (all P<0.05). No significant difference was found in ICNP, ICAP, ICVP, NIC and K between non-metastatic group nor benign hyperplasia group (all P>0.05). Conclusion Dual-source CT energy parameters can be used to qualitatively diagnose cervical enlarged lymph nodes after surgical resection of PTC.
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