| 刘大千,蒋南,侯开波,薛丹.经直肠超声联合精浆弹性蛋白酶诊断慢性精囊炎致男性不育[J].中国医学影像技术,2019,35(2):240~243 |
| 经直肠超声联合精浆弹性蛋白酶诊断慢性精囊炎致男性不育 |
| Transrectal ultrasound combined with seminal plasma elastase in diagnosis of male infertility caused by chronic seminal vesiculitis |
| 投稿时间：2018-06-01 修订日期：2018-10-30 |
| DOI：10.13929/j.1003-3289.201806006 |
| 中文关键词: 精囊炎 不育 超声检查 弹性蛋白酶 |
| 英文关键词:seminal vesiculitis infertility ultrasonography elastase |
| 基金项目:北部战区总医院和平分院课题（2017Y017）。 |
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| 中文摘要: |
| 目的 探讨经直肠超声联合精浆弹性蛋白酶（SPE）对诊断慢性精囊炎（CSV）致男性不育的价值。方法 对106例慢性精囊炎致男性不育患者（不育组）及106名健康男性（对照组）行经直肠超声检查及SPE检测，比较2组精囊超声参数及SPE的差异。分析SPE与精囊参数的相关性；建立ROC曲线，观察SPE联合精囊超声参数对CSV致男性不育的诊断效能。结果 不育组精囊短径、腺管内径、收缩期最大血流速度（PSV）、阻力指数（RI）及SPE水平均高于对照组（P均<0.01）。精囊短径、腺管内径、PSV、RI及SPE水平是慢性精囊炎致男性不育的影响因素（P均<0.05）。SPE与PSV、RI、精囊短径均呈正相关（r=0.732，P<0.001；r=0.647，P=0.004；r=0.526，P=0.007）。SPE联合PSV、RI及精囊短径均可用于诊断CSV致男性不育（P均<0.05），以SPE联合PSV的AUC最大为0.73，敏感度为0.73，特异度为0.70。结论 经直肠超声联合SPE对CSV致男性不育具有一定临床诊断价值。 |
| 英文摘要: |
| Objective To investigate the value of transrectal ultrasound combined with seminal plasma elastase (SPE) in diagnosis of male infertility caused by chronic seminal vesiculitis (CSV). Methods Transrectal ultrasonography was performed in 106 patients with male infertility caused by CSV (infertility group) and 106 healthy men (control group), and SPE was detected in two groups. The differences of seminal vesicle ultrasound parameters and SPE were compared between two groups. The correlations between SPE and seminal vesicle parameters were analyzed. ROC curves were used to evaluate the diagnostic efficiency of SPE combined with seminal vesicle ultrasound parameters on male infertility caused by CSV. Results The short diameter of seminal vesicle, inner diameter of gland tube, the peak systolic velocity (PSV), resistance index (RI) and SPE level in infertility group were higher than those in control group (all P<0.01). The short diameter of seminal vesicle, inner diameter of gland tube, PSV, RI and SPE were impact factors of male infertility caused by CSV (all P<0.05). SPE was positively correlated with PSV, RI and short diameter of seminal vesicle (r=0.732, P<0.001; r=0.647, P=0.004; r=0.526, P=0.007). SPE combined with PSV, RI and short diameter of seminal vesicle could be used to diagnose male infertility caused by CVS (all P<0.05), among which SPE combined with PSV had the most effective diagnostic value, the area under ROC was 0.73, the sensitivity and specificity was 0.73 and 0.70, respectively. Conclusion Transrectal ultrasound combined with SPE have certain clinical diagnostic value for male infertility induced by CSV. |
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