张汝森,张林启,何巧,李伟,李雯,任志刚,张书旭.99Tcm-MDP SPECT/CT诊断宫颈癌放疗后骨盆不全骨折[J].中国医学影像技术,2019,35(2):222~225
99Tcm-MDP SPECT/CT诊断宫颈癌放疗后骨盆不全骨折
99Tcm-MDP SPECT/CT in diagnosis of pelvic insufficiency fracture of cervical cancer after radiotherapy
投稿时间:2018-06-07  修订日期:2018-10-09
DOI:10.13929/j.1003-3289.201806029
中文关键词:  宫颈肿瘤  骨折,应力性  骨盆  体层摄影术,发射型计算机,单光子  放射性核素显像
英文关键词:uterine cervical neoplasms  facture, stress  pelvis  tomography, emission-computed, single-photon  radionuclide imaging
基金项目:广东省教育厅特色创新项目(2016KTSCX116)、广州市科技计划项目(A201804010297)。
作者单位E-mail
张汝森 广州医科大学附属肿瘤医院核医学科, 广东 广州 510095 zhangrusen2015@163.com 
张林启 广州医科大学附属肿瘤医院核医学科, 广东 广州 510095  
何巧 中山大学附属第一医院核医学科, 广东 广州 510055  
李伟 广州医科大学附属肿瘤医院核医学科, 广东 广州 510095  
李雯 广州医科大学附属肿瘤医院核医学科, 广东 广州 510095  
任志刚 广州医科大学附属肿瘤医院核医学科, 广东 广州 510095  
张书旭 广州医科大学附属肿瘤医院放疗中心, 广东 广州 510095  
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中文摘要:
      目的 探讨99Tcm-MDP SPECT/CT诊断宫颈癌放疗后骨盆不全骨折(PIF)的价值。方法 回顾性分析37例宫颈癌放疗后疑似PIF患者的全身显像(WBS)和骨盆SPECT/CT断层融合显像资料。以影像学资料、临床资料及随访(>12个月)结果作为最终诊断PIF的标准,比较WBS、SPECT/CT对PIF的诊断效能。结果 37例患者共50个骨盆病灶,最终诊断PIF 42个(30例)。WBS诊断PIF的灵敏度为45.24%(19/42),特异度50.00%(4/8),准确率46.00%(23/50);SPECT/CT诊断PIF的灵敏度为92.86%(39/42),特异度75.00%(6/8),准确率90.00%(45/50);SPECT/CT诊断宫颈癌放疗后PIF的灵敏度及准确率均高于WBS(χ2=22.28、22.24,P均<0.01),但二者特异度差异无统计学意义(P=0.31)。结论 99Tcm-MDP SPECT/CT可用于诊断宫颈癌放疗后PIF。
英文摘要:
      Objective To explore the value of 99Tcm-MDP SPECT/CT in diagnosis of pelvic insufficiency fracture (PIF) of cervical cancer after radiotherapy. Methods Whole body scan (WBS) and 99Tcm-MDP SPECT/CT data of 37 suspected PIF patients with cervical cancer after radiotherapy were retrospectively analyzed. The diagnosis standard of PIF was based on radiologic investigation, clinical information and follow up for at least 12 months. The efficiency in diagnosis of PIF was compared between WBS and SPECT/CT. Results Among 37 patients (50 pelvic lesions), 42 PIF lesions were diagnosed in 30 patients. The diagnostic sensitivity, specificity and accuracy of WBS diagnosis of PIF were 45.24% (19/42), 50.00% (4/8) and 46.00% (23/50), while of SPECT/CT diagnosis of PIF were 92.86% (39/42), 75.00% (6/8) and 90.00% (45/50), respectively. The diagnostic sensitivity and accuracy of SPECT/CT were significantly higher than those of WBS (χ2=22.28, 22.24, both P<0.01), and no significant difference of specificity was found between WBS and SPECT/CT (P=0.31). Conclusion 99Tcm-MDP SPECT/CT can be used for diagnosis of PIF.
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