| 张彦彦,张卫方.成人脊柱朗格汉斯细胞组织细胞增生症的18F-FDG PET/CT表现[J].中国医学影像技术,2019,35(1):134~137 |
| 成人脊柱朗格汉斯细胞组织细胞增生症的18F-FDG PET/CT表现 |
| 18F-FDG PET/CT manifestations of Langerhans cell histiocytosis in adult spine |
| 投稿时间：2018-05-14 修订日期：2018-09-22 |
| DOI：10.13929/j.1003-3289.201805081 |
| 中文关键词: 朗格汉斯细胞组织细胞增生症 脊柱 正电子发射断层显像术 氟脱氧葡萄糖F18 成人 |
| 英文关键词:langerhans cell histiocytosis spine positron-emission tomography Fluorodeoxyglucose F 18 adult |
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| 中文摘要: |
| 目的 观察成人脊柱朗格汉斯细胞组织细胞增生症（LCH）的18F-FDG PET/CT表现。方法 回顾性分析经病理证实的9例成人脊柱LCH患者的18F-FDG PET/CT表现，评估脊柱病灶数目、分布、密度、边界及最大标准摄取值（SUVmax）。结果 9例LCH共18个病灶位于脊柱，6例单发，3例多发。其中16个病灶18F-FDG PET/CT表现为不同程度的溶骨性骨质破坏及软组织密度肿块，边界清晰，7个可见边缘硬化，3个病变累及椎管；另2个病灶分别表现为片状稍高密度影及局部骨密度正常。所有病灶18F-FDG摄取均有不同程度增高，SUVmax为9.07±4.99。结论 成人脊柱LCH的18F-FDG PET/CT表现具有一定特征性，有助于诊断。 |
| 英文摘要: |
| Objective To observe 18F-FDG PET/CT manifestations of Langerhans cell histiocytosis (LCH) of the adult spine. Methods 18F-FDG PET/CT imaging features of 9 adult patients with LCH of spine confirmed by pathology were retrospectively analyzed. The lesions number, location, density, margin and the maximum standardized uptake (SUVmax) were observed. Results Among 9 cases (18 lesions of spine), single lesion was found in 6 patients, while multiple lesions were found in 3 patients. Sixteen lesions displayed different degrees of osteolytic bone destruction, with sharp margins and were filled with soft tissue, 7 lesions showed rim osteosclerosis, while 3 lesions invaded canalis vertebralis. Another 2 lesions were found as shape shadow of slightly high density and no density abnormity, respectively. High 18F-FDG uptake was found in all 18 lesions, the mean SUVmax was 9.07±4.99. Conclusion 18F-FDG PET/CT manifestations of LCH of adult spine have some characteristics, which are helpful to the diagnosis of this disease. |
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