| 宋桃桃,解丽梅.超声评价子痫前期患者胎儿主动脉峡部血流指数[J].中国医学影像技术,2018,34(11):1667~1671 |
| 超声评价子痫前期患者胎儿主动脉峡部血流指数 |
| Ultrasonic evaluation on fetal aortic isthmus flow index in preeclampsia patients |
| 投稿时间：2018-03-05 修订日期：2018-08-17 |
| DOI：10.13929/j.1003-3289.201803031 |
| 中文关键词: 主动脉峡 胎儿 子痫 血流指数 超声检查,多普勒,彩色 |
| 英文关键词:Aortic isthmus Fetus Eclampsia Flow index Ultrasonography, Doppler, color |
| 基金项目:辽宁省自然科学基金（2015020538）。 |
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| 中文摘要: |
| 目的 通过测量峡部血流指数（IFI）定量分析子痫前期（PE）患者胎儿主动脉峡部（AOI）血流变化特点与规律。方法 纳入38例PE患者（PE组）和孕周相匹配的38名正常单胎妊娠孕妇（对照组）。采集胎儿AOI、脐动脉（UA）、静脉导管（DV）的多普勒频谱，计算IFI，并分为Ⅰ~Ⅲ型，计算PE组胎儿AOI、UA舒张期血流及心房收缩波（DA-a）消失或反向率。结果 对照组胎儿IFI均为Ⅰ型，IFI值为1.40±0.09，AOI舒张期血流均为前向；PE组胎儿IFI Ⅰ型21胎，Ⅱ型10胎，Ⅲ型7胎，IFI值为0.81±0.80；2组IFI差异有统计学意义（t=4.439，P<0.001）。PE组胎儿AOI、UA舒张期血流和DV-a波消失或反向率分别为44.74%（17/38）、13.16%（5/38）和0，与对照组比较差异有统计学意义（χ2=25.796，P<0.001）。结论 PE患者胎儿IFI降低。检测胎儿AOI多普勒频谱可于胎儿循环缺氧早期检测其血流动力学变化。 |
| 英文摘要: |
| Objective To quantitatively evaluate the characteristics of fetal aortic isthmus (AOI) blood flow in preeclampsia (PE) patients with isthmus flow index (IFI). Methods Totally 38 PE patients (PE group) and 38 normal single pregnant women (control group) with matched gestational week were enrolled. Doppler waveforms of AOI, umbilical artery (UA) and ductus venosus (DV) were obtained. IFI was calculated and divided into type Ⅰ-Ⅲ. Also, the disappearance or reverse rate of fetal AOI and UA during diastolic blood flow and DV atrial contraction wave (DA-a) in PE group were calculated. Results IFI of all fetuses in control group were type Ⅰ, the IFI value was 1.40±0.09, and blood flow of AOI in diastole was forward. In PE group, type Ⅰ IFI was found in 21 fetuses, while type Ⅱ and type Ⅲ was detected in 10 and 7 fetuses, respectively, and the IFI value was 0.81±0.80. The difference of IFI between the 2 groups was statistically significant (t=4.439, P<0.001). In PE group, the rate of wave disappearance or reverse at fetal AOI, UA diastolic blood flow and DV-a was 44.74% (17/38), 13.16% (5/38) and 0, respectively, significantly different with those of control group (χ2=25.796, P<0.001). Conclusion The fetuses of PE patients show decreased IFI. Doppler spectrum of fetal AOI can display hemodynamic changes in early stage of fetal circulation hypoxia. |
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