| 钟婧,陈翠芳,陈英,林家豪,鲍道亮,陈韵彬.ADC值及相对ADC值鉴别诊断颈部淋巴瘤与转移性淋巴结[J].中国医学影像技术,2018,34(6):846~849 |
| ADC值及相对ADC值鉴别诊断颈部淋巴瘤与转移性淋巴结 |
| ADC and relative ADC in differential diagnosis of lymphoma and metastasis in cervical lymph nodes |
| 投稿时间：2017-11-03 修订日期：2018-04-01 |
| DOI：10.13929/j.1003-3289.201711020 |
| 中文关键词: 磁共振成像 淋巴瘤 表观扩散系数 淋巴转移 |
| 英文关键词:Magnetic resonance imaging Lymphoma Apparent diffusion coefficient Lymphatic metastasis |
| 基金项目:福建省科技厅引导性项目（2016Y0018）。 |
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| 中文摘要: |
| 目的 观察三维可变翻转角快速自旋回波（3D-SPACE）序列术前评估听神经瘤的价值。方法 收集经手术病理证实的听神经瘤患者57例，术前均接受脑部常规MR及3D-SPACE序列检查，观察3D-SPACE序列显示肿瘤位置、大小、形态等，评估其对相邻脑神经的显示率，并与常规MRI及手术所见相对照。结果 57例患者肿瘤均为单发，1例（1/57，1.75%）局限于内听道内，56例（56/57，98.25%）超出内听道口生长；26例（26/57，45.61%）充满内听道底，31例（31/57，54.39%）未充满内听道。57例中，3D-SPACE序列显示实质型肿瘤21例（21/57，36.84%），实质伴囊变型肿瘤35例（35/57，61.40%），囊型肿瘤1例（1/57，1.76%），与术中所见符合率为85.96%（49/57）。3D-SPACE序列对三叉神经脑池段、后组脑神经脑池段、展神经脑池段、面神经内听道段、面神经脑池段及听神经脑池段的显示率分别为100%（57/57）、100%（57/57）、75.44%（43/57）、50.88%（29/57）、17.53%（10/57）和19.30%（11/57），均高于常规MRI （P均<0.05）。结论 3D-SPACE序列可准确显示肿瘤与相邻脑神经的关系，对于术前评估听神经瘤具有重要临床价值。 |
| 英文摘要: |
| Objective To investigate the value of MR apparent diffusion coefficient (ADC) and relative apparent diffusion coefficient (rADC) in differential diagnosis of lymphoma and metastasis in cervical lymph nodes. Methods Totally 69 patients with lymphoma (lymphoma group) and 66 patients with cervical lymph nodes metastasis (metastasis group) underwent MR examination. ADC values of lymph nodes and the right masseter muscle were measured, and rADC values were calculated. The consistency between two observers was evaluated. The differences of ADC value and rADC value were compared between the two groups. The efficacy of ADC value and rADC value in differential diagnosis of lymphoma and metastasis in cervical lymph nodes was analyzed with ROC curve. Results The consistency between two observers was excellent (all ICC>0.9). Both ADC and rADC values of lymphoma group were significantly lower than those of metastasis group (all P<0.05). Taken ADC and rADC values as 0.702×10-3mm2/s and 0.584, the sensitivity and specificity was 98.48% and 89.39%, 76.81% and 84.06%, respectively. Conclusion ADC and rADC values are useful in discriminating lymphoma from metastatic lymph nodes. |
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