| 李海波,那曼丽,张滨,樊文鑫,于明川.冠状动脉CTA对冠状动脉粥样硬化性心脏病高危人群的随访观察价值[J].中国医学影像技术,2018,34(4):518~522 |
| 冠状动脉CTA对冠状动脉粥样硬化性心脏病高危人群的随访观察价值 |
| Value of coronary CTA in follow up observation for patients with high risks of coronary heart disease |
| 投稿时间：2017-03-08 修订日期：2018-02-27 |
| DOI：10.13929/j.1003-3289.201703028 |
| 中文关键词: 危险因素 冠状动脉疾病 体层摄影术,X线计算机 血管造影术 |
| 英文关键词:Risk factors Coronary artery disease Tomography,X-ray computed Angiography |
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| 中文摘要: |
| 目的 探讨冠状动脉CT血管成像（CCTA）对冠状动脉粥样硬化性心脏病（简称冠心病）高危险因素人群（简称高危人群）的随访观察价值。方法 选取于我院接受CCTA检查且空腹血糖、血脂（甘油三酯、总胆固醇、高密度脂蛋白及低密度脂蛋白）等生化指标及体质量指数有2项或2项以上异常的80例患者，经临床干预后，间隔2年再次行CCTA检查，同时行上述生化指标及体质量指数检测，根据两次CCTA检查结果分为稳定组和进展组，并对2组两次生化指标、体质量指数及其变化率进行统计学分析。结果 稳定组60例，进展组20例。进展组第1次与第2次检查高密度脂蛋白水平差异有统计学意义（t=2.64，P=0.02）；稳定组第2次检查体质量指数、血糖、甘油三酯、总胆固醇及低密度脂蛋白明显小于第1次检查（t=2.10、2.68、3.45、4.26、5.90，P=0.04、0.01、0.001、0.000 1、0.000 1）；进展组第2次检查甘油三酯（t=2.39，P=0.02）和低密度脂蛋白高于稳定组第2次检查（t=3.98，P<0.000 1）；进展组血糖变化率高于稳定组（t=-2.04，P=0.045）。结论 CCTA对于随访观察高危人群冠心病有积极的指导意义，通过加强对冠心病危险因素的积极干预，改变不良生活习惯，可以有效延缓或阻止冠心病的发生及发展。 |
| 英文摘要: |
| Objective To investigate the value of coronary CT angiography (CCTA) in the follow up observation of coronary heart disease in high-risk population. Methods Totally 80 coronary atherosclerotic plaque patients underwent CCTA. The fasting blood sugar, blood lipid (triglycerides, total cholesterol, high-density lipoprotein, low-density lipoprotein) and body mass index of all patients showed two or more abnormalities. After clinical intervention, CCTA examination, serum biochemical indexes and body mass index were tested again two years later. According to the degree of coronary artery stenosis quantitative assessment results, the patients were divided into stable group and progress group. All parameters before and after the two checks were statistically analyzed. Results According to the results of CCTA, stable group included 60 cases and progress group included 20 cases. The statistically significant difference was found between the first and second examination of high-density lipoprotein in the progress group were (t=2.64, P=0.02). The body mass index, blood glucose, triglycerides, total cholesterol and low-density lipoprotein (LDL) of the second test in stable group were significantly lower than those of the first check (t=2.10, 2.68, 3.45, 4.26, 5.90, P=0.04, 0.01, 0.001, 0.000 1, 0.000 1), while triglyceride (t=2.39, P=0.02) and LDL in the second check in progress group were both higher than those of the second check in stable group (t=3.98, P<0.000 1), and the rate of change of blood sugar in the progress group was higher than that in the stable group (t=-2.04, P=0.045). Conclusion CCTA plays positive role in the follow up observation of high-risk population of coronary heart disease. Guiding the active intervention of the risk factors and promoting the patients to change the bad habits can effectively delay or prevent the occurrence and development of coronary heart disease. |
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