戴晨燕,茹彤,顾燕,杨燕,徐燕.产前超声诊断胎儿单侧多囊性发育不良肾[J].中国医学影像技术,2017,33(3):437~439
产前超声诊断胎儿单侧多囊性发育不良肾
Prenatal ultrasound in diagnosis of fetal unilateral polycystic kidney disease
投稿时间:2016-10-11  修订日期:2016-12-10
DOI:10.13929/j.1003-3289.201610036
中文关键词:  超声检查,产前  多囊性肾发育不良
英文关键词:Ultrasonography, prenatel  Multicystic dysplastic kidney
基金项目:国家"十二五"科技支撑计划课题项目(2014BAI06B05)、江苏省产前筛查及产前诊断现状调查与技术规范的研究推广(H201340)。
作者单位E-mail
戴晨燕 南京大学医学院附属鼓楼医院产前诊断中心, 江苏 南京 210008  
茹彤 南京大学医学院附属鼓楼医院产前诊断中心, 江苏 南京 210008 15380951881@163.com 
顾燕 南京大学医学院附属鼓楼医院产前诊断中心, 江苏 南京 210008  
杨燕 南京大学医学院附属鼓楼医院产前诊断中心, 江苏 南京 210008  
徐燕 南京大学医学院附属鼓楼医院产前诊断中心, 江苏 南京 210008  
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中文摘要:
      目的 探讨超声检查诊断单纯性单侧多囊性发育不良肾(MCDK)的价值。方法 回顾性分析于我院产前诊断中心进行产前系统超声筛查检出的29胎单纯性单侧MCDK胎儿。在排除孕妇妊娠合并征、胎儿合并有其他结构异常及胎儿染色体核型异常后,对其中15胎继续妊娠并进行随访的胎儿跟踪观察至产后,观察胎儿患侧肾脏的声像图变化特征、健侧肾脏形态及大小、患儿生长发育及肾功能有无受损。结果 15胎单侧MCDK胎儿,最短随访时间为孕期至出生后7个月,最长随访时间为孕期至患儿5周岁。超声显示胎儿时期患侧肾脏体积常先变大,至妊娠晚期近足月时肾脏体积多逐渐缩小,至出生后5~6个月时患侧肾脏常已萎缩,甚至超声无法探及。而健侧肾脏的形态、大小、声像图特征与正常同孕龄胎儿相似。产前胎儿生长发育指标及羊水量均在正常。出生后,除1例患儿体质量过重外,其余患儿的生长发育指标均在正常范围。结论 胎儿单纯性单侧MCDK多预后良好,超声在检查及随访中有重要价值,可为产前诊断咨询提供可靠依据。
英文摘要:
      Objective To investigate the value of ultrasound in diagnosis of fetal simple unilateral multicystic dysplastic kidney (MCDK) disease. Methods Pregnant women who underwent prenatal ultrasound screening and follow-up were analyzed retrospectively, and 29 fetues with MCDK were found. After exclusion of pregnancy syndrome, other structural abnormalities and chromosomal abnormalities, 15 fetues willing to continue pregnancy and accepting the follow-up tracking observation were observed to postpartum. Ipsilateral renal ultrasonographic characteristics, contralateral renal morphology and size, growth and development of children and the renal function were analyzed. Results The minimum follow-up time of the 15 fetus was pregnancy to 7 months after birth, the maximum follow-up time was pregnancy to 5 years of age in children. Ultrasound showed that ipsilateral kidney volume became large in fetal period, reduced gradually in late pregnancy, and atrophy in 5-6 months after birth, even could not displayed with untrasound. The shape, size, and sonographic characteristics of the healthy kidney were similar to the normal gestational age kidney. Prenatal fetal growth indicators and amniotic fluid volume were normal. After birth, except for 1 child with overweight, other children's growth and development indicators were almost normal. Conclusion Fetus with simple unilateral MCDK has a good prognosis. Ultrasound has important value in the examination and follow-up. It can provide reliable basis for prenatal diagnosis and consultation.
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