| 鄢磊,许翔,叶小剑,王行富,陈晓宇,徐荣全.含有鳞状细胞癌成分的乳腺化生性癌的超声与病理特征[J].中国医学影像技术,2017,33(3):410~413 |
| 含有鳞状细胞癌成分的乳腺化生性癌的超声与病理特征 |
| Ultrasonographic and pathological features of metaplastic carcinoma with squamous cell component of breast |
| 投稿时间：2016-08-30 修订日期：2016-12-26 |
| DOI：10.13929/j.1003-3289.201608140 |
| 中文关键词: 超声检查 乳腺肿瘤 化生性癌 鳞状细胞癌 病理学 |
| 英文关键词:Ultrasonography Breast neoplasms Metaplastic carcinoma Squamous cell carcinoma Pathology |
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| 中文摘要: |
| 目的 观察含有鳞状细胞癌成分的乳腺化生性癌（MCSC）的声像图和病理学特征。方法 回顾性分析7例经手术病理检查证实的MCSC患者的二维声像图及CDFI声像图特征，并与病理学表现进行对照分析。结果 7例MCSC病灶均为单发；最大径2.6~5.1 cm；6例为混合回声，1例为低回声，6例病灶内均可见大小不一的无回声区；7例形态均呈微小或小分叶状、边缘模糊。CDFI显示病灶实性部分有较丰富血流，4例为Ⅲ级血流信号，2例为Ⅱ级血流信号，1例为Ⅰ级血流信号，频谱显示为高阻力动脉血流（阻力指数0.75~0.97）。术后病理大体标本示6例为囊实性，1例为实性，镜下病理5例表现为腺鳞癌，2例表现为纯鳞状细胞癌。免疫组化显示雌、孕激素受体和人表皮生长因子受体均为阴性者（三阴乳腺癌）4例。结论 MCSC声像图特征为体积较大、囊实性混合回声、瘤体后方回声增强、实性回声内血供丰富且动脉阻力高。 |
| 英文摘要: |
| Objective To observe the ultrasonographic and pathological features of metaplastic carcinoma with squamous cell component (MCSC) of the breast. Methods The ultrasonographic and pathological features of 7 patients with breast MCSC confirmed pathologically were retrospectively analyzed. Results Seven cases were single lesion and the maximal diameters of the lesions were 2.6-5.1 cm. On two-dimensional imaging, 6 lesions with cystic and solid were complex echogenic, only 1 lesion was hypoechoic. All the lesions had irregular shape (lobulated)and indistinct margin. On CDFI imaging, most of lesions had rich blood flow signals with high resistance (resistance index 0.75-0.91), 4 lesions were grade Ⅲ, 2 lesions were grade Ⅱ and 1 lesion was grade Ⅰ blood flow signals. On gross histopathological examination, 6 masses had cystic cavity, only 1 mass was pure solid. On microscopic histopathological examination, 5 masses were adenosquamous carcinoma, only 2 masses were pure squamous cell carcinoma. Estrogen receptors, progesterone receptors and human epidermal growth factor receptor were negative in 4 masses (triple-negative breast cancer). Conclusion MCSC have some distinguished ultrasonic characteristics of larger volume, cystic-solid mixed echo, posterior echo enhancement, abundant vascularity with high resistance. |
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