| 杨静,陈新燕,吴永娟.超声评价放疗对颈动脉溃疡斑块形成的影响[J].中国医学影像技术,2017,33(3):381~385 |
| 超声评价放疗对颈动脉溃疡斑块形成的影响 |
| Ultrasonic evaluation of effect of radiotherapy of plaque ulcer of carotid artery |
| 投稿时间：2016-08-04 修订日期：2016-12-23 |
| DOI：10.13929/j.1003-3289.201608024 |
| 中文关键词: 超声检查 颈动脉 溃疡斑块 放射治疗 |
| 英文关键词:Ultrasonography Carotid artery Ulcer plaque Radiotherapy |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨超声在评价放疗对颈动脉溃疡斑块形成的影响的价值。方法 回顾性收集经病理学证实为头颈部肿瘤、放疗前后的颈动脉超声资料以及其他基线资料完整的患者93例，比较放疗前后放疗侧颈动脉和非放疗侧颈动脉粥样硬化斑块和溃疡斑块的总数量、平均内膜-中膜厚度、最大斑块面积、最大溃疡斑块的面积、最大溃疡口的面积。结果 放疗前后颈动脉超声检查的平均间隔时间为（6.1±1.9）年；放疗前放疗侧斑块总数量、平均内膜-中膜厚度、最大斑块面积、溃疡斑块的总数量、最大溃疡斑块的面积、最大溃疡口的面积与非放疗侧比较差异均无统计学意义（P均>0.05）；放疗后放疗侧斑块总数量、平均内膜-中膜厚度、最大斑块面积、溃疡斑块的总数量、最大溃疡斑块的面积、最大溃疡口的面积均较非放疗侧加重，差异有统计学意义（P均<0.05）。结论 放疗可导致头颈部肿瘤患者颈动脉粥样硬化斑块的形成和进展，且斑块具有易损性特点。 |
| 英文摘要: |
| Objective To investigate the effect of radiotherapy on carotid plaque ulcer formation by using ultrasound imaging. Methods Totally 93 cases diagnosed with head and neck cancers which had complete carotid ultrasound data and other baseline data before and after radiotherapy (RT) were retrospectively enrolled. The total number of plaques, average intima-media thickness, maximum plaque area, total number of ulcer plaques, maximum ulcer plaque area and the maximum area of the ulcer pit were compared in RT side and non-RT side before and after RT respectively. Results The average interval time was 6.1±1.9 years between twice RT. Before RT, there were no statistical differences between RT side and non-RT side in the total number of plaques, the average intima-media thickness, maximum plaque area, total number of ulcer plaques, maximum ulcer plaque area and maximum area of the ulcer pit. After RT, compared with those of non-RT side, there were more lesions of the total number of plaques, the thicker average intima-media thickness, the larger maximum plaque area, the more maximum number of ulcer plaques, the larger maximum ulcer plaque area and maximum area of the ulcer pit in RT side, which had statistical defference (all P<0.05). Conclusion RT can lead to the formation and progression of carotid atherosclerotic plaque in patients with head and neck cancers, and the plaque has a vulnerability characteristics. |
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