| 方元,管宇,夏艺,范丽,刘士远,肖湘生.CT定量评估肺气肿的研究进展[J].中国医学影像技术,2017,33(1):132~136 |
| CT定量评估肺气肿的研究进展 |
| Research progresses in CT quantitative assessment of emphysema |
| 投稿时间：2016-07-08 修订日期：2016-10-26 |
| DOI：10.13929/j.1003-3289.201607039 |
| 中文关键词: 体层摄影术,X线计算机 肺气肿 定量 肺功能检查 |
| 英文关键词:Tomography,X-ray computed Emphysema Quantification Pulmonary function test |
| 基金项目:国家自然科学基金重点项目（81230030）、国家自然科学基金面上项目（81370035）、国家自然科学基金青年项目（81501470、81501618）、上海市浦江人才计划（15PJD002）。 |
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| 中文摘要: |
| 肺气肿是指肺部终末细支气管远端出现的异常持久扩张，伴有肺泡壁和细支气管破坏但无明显的肺纤维化，晚期时严重影响呼吸功能，病死率高。目前临床上常用肺功能检查（PFT）评价肺气肿，但其具有一定局限性。CT可较好地显示肺气肿的分布、程度和范围，其对肺气肿的定量评估主要有主观半定量法和客观法。随着CT技术的发展，其定量评估肺气肿的准确率越来越高，并与PFT具有良好的相关性。采取CT定量评估与PFT相结合的方式可更加全面地评价肺气肿，更好地指导临床诊治。 |
| 英文摘要: |
| Emphysema is the abnormal expansion of the terminal bronchioles, and accompanied by the destruction of alveolar walls and bronchioles with no obvious pulmonary fibrosis. The mortality of emphysema is extremely high with the impairment of respiratory function in advanced stage. Pulmonary function test (PFT) has some limitations in assessment of emphysema. CT scan shows a good reflection in distribution, degree and scope of emphysema. The methods of CT quantitative assessment are divided into subjective semi-quantitative method and objective method. With the improvement of CT technology, the accuracy of CT quantitative assessment is higher, and has a good correlation with PFT. CT quantitative assessment combined with PFT can make a more comprehensive evaluation of emphysema and can guide clinical diagnosis and treatment. |
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