成东亮,胡培铅,胡译心,文戈.原发性支气管黏液表皮样癌的临床及CT特征[J].中国医学影像技术,2017,33(1):44~48
原发性支气管黏液表皮样癌的临床及CT特征
Clinical and multi-slice CT features of primary pulmonary mucoepidermoid carcinoma
投稿时间:2016-06-20  修订日期:2016-08-02
DOI:10.13929/j.1003-3289.201606097
中文关键词:    癌,黏液表皮样  体层摄影术,X线计算机  病理学
英文关键词:Lung  Carcinoma,mucoepidermoid  Tomography,X-ray computed  Pathology
基金项目:
作者单位E-mail
成东亮 南方医科大学南方医院影像中心, 广东 广州 510515  
胡培铅 南方医科大学南方医院影像中心, 广东 广州 510515  
胡译心 南方医科大学南方医院影像中心, 广东 广州 510515  
文戈 南方医科大学南方医院影像中心, 广东 广州 510515 wenge1967@qq.com 
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中文摘要:
      目的 探讨原发性支气管黏液表皮样癌(PMEC)的临床及CT特征。方法 回顾性分析经病理证实的33例PMEC的临床及CT资料。结果 33例PMEC中,低级别18例(男7例、女11例),高级别15例(男12例、女3例)。CT表现:周围型17例(低级别6例、高级别11例),中央型16例(低级别12例、高级别4例);24例肿块长径与所属肺叶或肺段支气管平行;肿块密度欠均匀,18例肿块内见低密度区;阻塞性表现14例,5例见“空气新月征”,钙化3例;对29例行增强扫描,其中轻度强化19例,中度及显著强化各5例。高、低级别PMEC的好发性别、分布和淋巴结肿大表现上的差异有统计学意义(P均<0.05),高级别PMEC淋巴结转移率高于低级别PMEC,但差异无统计学意义(P>0.05)。结论 不同病理级别PMEC在好发性别上有一定倾向性。CT图像上PMEC呈边界清晰的类圆形或分叶状,阻塞性表现及钙化常见,多呈轻度不均匀强化。高级别PMEC多为外周型,淋巴结转移较常见,低级别PMEC多为中央型,淋巴结转移少见。
英文摘要:
      Objective To explore the clinical features and the multi-slice CT (MSCT) findings of primary pulmonary mucoepidermoid carcinoma (PMEC). Methods Clinical and CT data were analyzed retrospectively in 33 patients with pathology proved PMEC. Results In the 33 cases of PMEC, 18 cases were low grade (7 males and 11 females) and 15 cases were high grade (12 males and 3 females). On the CT images, 17 peripheral tumors (6 cases of low grade, 11 cases of high grade) and 16 central tumors (12 cases of low grade, 4 cases of high grade) were identified. Long axis in 24 cases were parallel to the affiliated segmental or lobar bronchi. The density of tumors were heterogeneous, low density regions in the lesions or distal bronchi could be seen in 18 cases. Besides, additional findings such as distal obstructive performance (n=14), "air crescent sign" (n=5) and visible punctate calcification (n=3) could be seen. On enhanced scan (n=29), 19 cases showed mild enhancement and 5 cases showed moderate and significant enhancement respectively. There were significant differences in the gender and presence of lymphadenopathy between high and low grade PMEC (both P<0.05). Though lymph node metastasis rate of high grade PMEC was higher than that of low grade PMEC, the difference was not statistically significant (P>0.05). Conclusion It shows gender predilection between different grades PMEC. On CT imgaes, an oval or lobulated mass with mild enhancement calcification and obstructive performance may be suggestive of PMEC. High grade PMECs tend to be peripheral. Besides, lymph node metastasis is more commonly seen. On the contrary, a central bronchial nodule or mass without lymph node metastasis may suggest low grade PMEC.
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