宋乐,张卫方,张燕燕,赵梅莘,侯小艳.18F-FDG PET/CT诊断静脉瘤栓[J].中国医学影像技术,2016,32(11):1688~1692
18F-FDG PET/CT诊断静脉瘤栓
18F-FDG PET/CT in diagnosis of venous tumor thrombus
投稿时间:2016-04-01  修订日期:2016-08-17
DOI:10.13929/j.1003-3289.2016.11.016
中文关键词:  瘤栓  氟脱氧葡萄糖F18  正电子发射断层显像术  体层摄影术,X线计算机
英文关键词:Tumor thrombus  Fludeoxyglucose F 18  Positron-emission tomography  Tomography, X-ray computed
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作者单位E-mail
宋乐 北京大学第三医院核医学科, 北京 100191  
张卫方 北京大学第三医院核医学科, 北京 100191 tsy1997@126.com 
张燕燕 北京大学第三医院核医学科, 北京 100191  
赵梅莘 北京大学第三医院核医学科, 北京 100191  
侯小艳 北京大学第三医院核医学科, 北京 100191  
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中文摘要:
      目的 探讨18F-FDG PET/CT对静脉瘤栓的诊断价值。方法 回顾性分析34例静脉瘤栓患者的PET/CT资料,观察瘤栓放射性摄取程度及形态学改变,测量瘤栓及原发肿瘤的最大标准化摄取值(SUVmax)。按照美国Mayo Clinic瘤栓分级标准,采用PET/CT及增强CT分别对20例肾脏肿瘤导致的下腔静脉瘤栓进行分级。分析静脉瘤栓与原发肿瘤SUVmax的相关性和PET/CT与增强CT对瘤栓分级的一致性。结果 瘤栓共累及53个静脉节段,以下腔静脉(n=16)、肾静脉(n=16)及门静脉(n=7)为主;瘤栓代谢高于血池本底51个,等于或低于血池本底各1个;48个呈条状,5个呈结节状;41个伴静脉增宽,31个患者瘤栓与原发肿瘤相延续。静脉瘤栓平均SUVmax为7.54±5.06,原发肿瘤平均SUVmax为9.25±6.17,二者呈正相关(r=0.76,P<0.001)。PET/CT明确诊断静脉瘤栓31例,诊断正确率为91.18%(31/34)。PET/CT与增强CT对瘤栓分级的一致性较好(Kappa=0.87,P<0.001)。结论 18F-FDG PET/CT对静脉瘤栓具有良好的诊断价值。
英文摘要:
      Objective To investigate the diagnostic value of 18F-FDG PET/CT in diagnosis of venous tumor thrombus (VTT). Methods The PET/CT data of 34 patients with VTT were reviewed. The maximal standard uptake value (SUVmax) of VTT and primary tumors, the morphological features of VTT were analyzed. PET/CT and contrast enhanced CT were used respectively to classify inferior vena cava tumor thrombus, according to the criteria of Mayo Clinic. The correlation of SUVmax between VTT and primary tumor, as well as the consistency of VTT classification between PET/CT and contrast enhanced CT were analyzed. Results Totally 53 venous segments were involved by tumor thrombus, most of which were inferior vena cava (n=16), renal vein (n=16) and portal vein (n=7) respectively. Fifty-one segments of VTT increased, one equaled and one decreased FDG activity compared with blood pool respectively. VTT were linear in 48 segments, focal in 5 segments. Forty-one segments were dilated. VTT were continued with primary tumors in 31 patients. The mean SUVmax of VTT was 7.54±5.06, and that of primary tumors was 9.25±6.17. There was a positive correlation between the mean SUVmax of VTT and primary tumors (r=0.76, P<0.001). The diagnostic accuracy of PET/CT was 91.18% (31/34). PET/CT had a good consistency with contrast enhanced CT in classification of VTT (Kappa=0.87, P<0.001). Conclusion 18F-FDG PET/CT is a valuable modality in diagnosis of venous tumor thrombus.
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