| 王璆,丁康,张立霞,梁俊媚,刘强.左心房容积追踪技术评价单支冠状动脉狭窄患者左心房容积和功能变化[J].中国医学影像技术,2016,32(10):1499~1503 |
| 左心房容积追踪技术评价单支冠状动脉狭窄患者左心房容积和功能变化 |
| Left atrial volume tracking technique in assessment of left atrial volume and function changes in patients with single coronary artery stenosis |
| 投稿时间：2016-05-12 修订日期：2016-07-19 |
| DOI：10.13929/j.1003-3289.2016.10.007 |
| 中文关键词: 冠状动脉狭窄 心房,左 超声心动描记术 容积追踪 |
| 英文关键词:Coronary stenosis Atrial, left Echocardiography Volume tracking |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨左心房容积追踪（LAVT）技术评价单支冠状动脉狭窄（CAS）患者左心房容积和功能变化的临床应用价值。方法 收集冠状动脉左前降支（LAD）狭窄患者22例（LAD组）、冠状动脉左回旋支（LCX）狭窄患者17例（LCX组）及CAS率<30%的患者30例（对照组）。获取心尖四腔及两腔动态超声图像。采用LAVT技术生成双平面左心房容积-时间曲线和容积变化速率曲线，获得左心房最大容积（LAVmax）、收缩前容积（LAVp）、最小容积（LAVmin）、左心房收缩期充盈速率峰值（dv/dtS）、舒张早期排空速率峰值（dv/dtE）、舒张晚期排空速率峰值（dv/dtA）。将容积参数采用体表面积校正后获得相应的指数（LAVImax、LAVIp、LAVImin），计算左心房总排空率（LAtE）、被动排空率（LApE）、主动排空率（LAaE），并进行统计学分析。结果 3组LAVImax、LAVIp、LAVImin比较，差异均有统计学意义（P均<0.05）。LAD组和LCX组LAVImax、LAVIp、LAVImin均大于对照组（P均<0.05）。LCX组LAVImax、LAVIp、LAVImin均大于LAD组（P均<0.05）。3组LAtE、LApE、LAaE、dv/dtS、dv/dtE和dv/dtA比较，差异均有统计学意义（P均<0.05）。LAD组和LCX组LAtE、LApE、dv/dtS、dv/dtE均小于对照组（P均<0.05），LAD组LAaE、dv/dtA均大于对照组（P均<0.05），LCX组LAaE、dv/dtA均小于对照组（P均<0.05）。LCX组LAtE、LApE、LAaE、dv/dtS、dv/dtE、dv/dtA均小于LAD组（P均<0.05）。结论 LAVT可准确评价单支CAS患者左心房的容积和功能变化。LCX狭窄较LAD狭窄的左心房容积和功能变化更为显著。 |
| 英文摘要: |
| Objective To investigate the clinical application value of left atrial volume tracking (LAVT) technique in assessment of left atrial volume and function changes in patients with single coronary artery stenosis (CAS).Methods Twenty-two left anterior descending coronary artery (LAD) stenosis patients (LAD group), 17 left circumflex coronary artery (LCX) stenosis patients (LCX group) and 30 CAS rate <30% patients (control group) were enrolled. Two-chamber and four-chamber dynamic ultrasound images of patients were obtained. Left atrial volume-time curve and volume change velocity curve were obtained by LAVT. Maximal left atrial volume (LAVmax), pre-systolic left atrial volume (LAVp), minimal left atrial volume (LAVmin), peak filling rate of left atrial in systolic (dv/dtS), peak emptying rate of left atrial in early diastolic (dv/dtE), peak emptying rate of left atrial in late diastolic (dv/dtA) were also recorded. After volume parameters were adjusted by body surface area, the index of LAVmax, LAVp and LAVmin (LAVImax, LAVIp and LAVImin) were obtained, the left atrial total emptying rate, left atrial passive emptying rate and left atrial active emptying rate were calculated, and the statistical analysis was performed.Results There were significant differences in LAVImax, LAVIp, LAVImin among three groups (all P<0.05). LAVImax, LAVIp, LAVImin in LAD group and LCX group were larger than those in control group (all P<0.05). LAVImax, LAVIp, LAVImin in LCX group were larger than those in LAD group (all P<0.05). There were statistical differences in LAtE, LApE, LAaE, dv/dtS, dv/dtE and dv/dtA among three groups (all P<0.05). LAtE, LApE, dv/dtS, dv/dtE in LAD group and LCX group were smaller than those in control group (all P<0.05). LAaE, dv/dtA in LAD group were larger than those in control group (all P<0.05), LAaE, dv/dtA in LCX group were smaller than those in control group (all P<0.05). LAtE, LApE, LAaE、dv/dtS, dv/dtE, dv/dtA in LCX group were smaller than those in LAD group (all P<0.05).Conclusion The changes of left atrial volume and function in single CAS patients can be evaluated accurately by LAVT. Left atrial volume and function changes are more obvious in LCX stenosis than LAD stenosis. |
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