白岩,姜兴岳,张洁,石清磊,聂泰明,杨明瑞,郑蕾.3.0T RESOLVE-DWI与SS-EPI DWI在大鼠颅脑成像中的对比分析[J].中国医学影像技术,2016,32(9):1325~1329
3.0T RESOLVE-DWI与SS-EPI DWI在大鼠颅脑成像中的对比分析
Comparative analysis between 3.0T RESOLVE-DWI and SS-EPI DWI in rats with brain glioma
投稿时间:2015-12-21  修订日期:2016-05-11
DOI:10.13929/j.1003-3289.2016.09.003
中文关键词:  胶质瘤  扩散磁共振成像  动物实验
英文关键词:Golima  Diffusion magnetic resonance imaging  Animal experimentation
基金项目:山东省自然科学基金(ZR2011HL038)。
作者单位E-mail
白岩 滨州医学院附属医院影像科, 山东 滨州 256603  
姜兴岳 滨州医学院附属医院影像科, 山东 滨州 256603 xyjiang188@sina.com 
张洁 滨州医学院附属医院影像科, 山东 滨州 256603  
石清磊 西门子(中国)有限公司磁共振产品事业部, 北京 100102  
聂泰明 滨州医学院附属医院影像科, 山东 滨州 256603  
杨明瑞 滨州医学院附属医院影像科, 山东 滨州 256603  
郑蕾 滨州医学院附属医院影像科, 山东 滨州 256603  
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中文摘要:
      目的 探讨高分辨率扩散加权成像(RESOLVE-DWI)在大鼠颅脑胶质瘤成像中的应用价值。方法 选取20只Wistar大鼠建立C6胶质瘤模型,并进行常规MRI、单次激发平面回波成像(SS-EPI) DWI及RESOLVE-DWI序列扫描。分别计算SS-EPI DWI和RESOLVE-DWI图像的SNR、CNR及ADC值,评价图像畸变程度,对图像质量进行主观评分,并进行统计学分析。结果 RESOLVE-DWI解剖结构显示规则,颅脑结构轮廓更加接近真实颅脑结构。RESOLVE-DWI图像的SNR及CNR均明显高于SS-EPI DWI(P均<0.05)。RESLOVE-DWI图像评分高于SS-EPI DWI(P<0.05)。RESLOVE-DWI与SS-EPI DWI图像肿瘤中心区和对侧正常脑组织ADC值差异均无统计学意义(P均>0.05)。RESLOVE-DWI和SS-EPI DWI图像中肿瘤中心区ADC值均明显高于对侧正常脑组织(P均>0.05)。结论 RESOLVE-DWI可提供满足临床诊断需求的DWI及ADC图像,较SS-EPI DWI图像质量明显提高。
英文摘要:
      Objective To explore the applicative value of readout segmentation of long variable echo-trains DWI (RESOLVE-DWI) in rats with brain glioma. Methods Twenty Wistar rats were collected to establish C6 glioma model. Conventional MRI, RESOLVE-DWI, and single-shot echo planer imaging (SS-EPI) DWI were performed. SNR, CNR and ADC value of SS-EPI DWI and RESOLVE-DWI were calculated, and the distortion of the images were evaluated. Statistical analysis was carried out. Results The anatomical structure of RESLOVE-DWI was displayed regular, and it was more close to the real brain structure. SNR and CNR of RESLOVE-DWI were higher than those of SS-EPI DWI (P<0.05). The subjective score of RESLOVE-DWI was obviously higher than that of SS-EPI DWI (P<0.05). ADC values of tumor and contralateral normal brain tissue between RESLOVE-DWI and SS-EPI DWI had no statistical difference (both P>0.05). ADC values of tumor were higher than those of contralateral normal brain tissue in both of RESLOVE-DWI and SS-EPI DWI (both P<0.05). Conclusion RESOLVE-DWI can provide DWI and ADC images which meet the needs of clinical diagnosis, and image quality is higher than that of SS-EPI DWI.
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